NATIONAL AND STATE NURSING EXAM- MCQ _MG_0078
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1. Blood cells are formed at……..organs:
a. Liver
b. Thymus
c. Red bone marrow
d. Spleen
Answer: c. Red bone marrow
Description:Blood cells are formed through a process called hematopoiesis, which occurs in the red bone marrow of certain bones in the human body. Red bone marrow is a soft tissue found primarily in the spongy or cancellous portions of bones, such as the ribs, sternum, vertebrae, and pelvis. Within the red bone marrow, hematopoietic stem cells undergo differentiation and maturation to produce various types of blood cells, including red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). These blood cells are vital for carrying oxygen, fighting infections, and aiding in blood clotting, respectively. While the liver and spleen are involved in the breakdown and removal of old or damaged blood cells, they are not organs where blood cells are formed. The thymus, on the other hand, plays a role in the maturation of certain types of white blood cells (T lymphocytes), but it does not produce blood cells.
2. The functions of the lymphatic system include all of the following; EXCEPT:
a. Maintaining tissue fluid balance
b. Functioning as body’s defense system
c. Absorbing fat and other substances from the digestive system
d. Producing red blood cells.
Answer: d. Producing red blood cells.
Description:The lymphatic system does not produce red blood cells. The primary functions of the lymphatic system include: a. Maintaining tissue fluid balance: The lymphatic system helps to regulate the fluid balance in tissues by collecting excess interstitial fluid and returning it to the bloodstream. b. Functioning as the body's defense system: The lymphatic system plays a crucial role in the body's immune response. Lymphatic vessels transport lymph, which contains immune cells, to lymph nodes where pathogens, toxins, and other foreign substances are filtered out and destroyed. c. Absorbing fat and other substances from the digestive system: Specialized lymphatic vessels called lacteals in the small intestine absorb dietary fats and fat-soluble vitamins. The absorbed fats are transported via lymphatic vessels to the bloodstream. However, it's important to note that the production of red blood cells occurs in the bone marrow, specifically in the spongy or cancellous bone marrow found in the ends of long bones and in the flat bones such as the sternum, ribs, and pelvis.
3. The process that assists in the transport of lymph includes
a. Gravity
b. Blood moving through the arteries
c. Blood moving through the veins
d. Contraction of the surrounding skeletal muscles
Answer: d. Contraction of the surrounding skeletal muscles
Description: Contraction of the surrounding skeletal muscles assists in the transport of lymph. Lymph is a fluid that circulates throughout the lymphatic system, which plays a vital role in immune function and fluid balance in the body. Unlike the cardiovascular system, the lymphatic system does not have a central pump like the heart to propel lymph. Instead, the movement of lymph relies on various mechanisms, including the contraction of skeletal muscles. When skeletal muscles contract during physical activity or movement, they exert pressure on the lymphatic vessels, helping to push the lymph forward. The other options listed, a, b, and c, are not directly involved in the transport of lymph. While gravity may influence the direction of lymph flow, it is not a primary mechanism for its transport. Blood moving through the arteries and veins is separate from the movement of lymph, although the close proximity of the two systems allows for some exchange of fluid and waste products between them.
4. Substances that stimulate an acquired immunity response are called:
a. Antigens
b. Antibodies
c. Complements
d. Histamines
Answer: a. Antigens
Description:Substances that stimulate an acquired immunity response are called antigens. Antigens are molecules that can be recognized by the immune system as foreign or non-self, leading to the activation of an immune response. The immune system produces specific molecules called antibodies in response to antigens, which help in neutralizing or eliminating the antigen.
5. Antibody-mediated immunity is effective against:
a. Bacteria
b. Viruses
c. Toxins
d. All of these
Answer: d. All of these
Description:Antibody-mediated immunity is effective against all of these options: bacteria, viruses, and toxins. Antibodies, also known as immunoglobulins, are produced by B cells of the immune system in response to the presence of foreign substances, such as pathogens or toxins. These antibodies can recognize and bind to specific antigens on the surface of bacteria or viruses, marking them for destruction by other components of the immune system. Additionally, antibodies can neutralize toxins produced by certain bacteria or other organisms, rendering them harmless. Therefore, antibody-mediated immunity plays a crucial role in defending the body against various types of infections and toxins.
6. “Prothrombin time†of plasma is prolonged by administration of:
a. Vitamin K
b. Dicoumarol
c. Calcium and vitamins
d. Proteins and minerals
Answer: b. Dicoumarol
Description:Prothrombin time (PT) is a test used to evaluate the clotting ability of blood. It measures the time it takes for a blood sample to clot in response to certain clotting factors. The administration of dicoumarol, an anticoagulant medication, can prolong the prothrombin time. Dicoumarol belongs to a class of drugs known as vitamin K antagonists. It works by inhibiting the action of vitamin K, which is necessary for the production of several clotting factors, including prothrombin. By interfering with the normal function of vitamin K, dicoumarol effectively prolongs the prothrombin time. Vitamin K (option a) actually plays a role in the production of clotting factors, including prothrombin. Therefore, the administration of vitamin K would not prolong the prothrombin time but rather help in its production and reduce the time. Calcium and vitamins (option c) as well as proteins and minerals (option d) do not have a direct effect on the prothrombin time. While calcium is involved in the clotting process, its administration alone would not significantly affect the prothrombin time. Similarly, proteins and minerals are essential for overall health but do not directly impact the clotting process or the prothrombin time.
7. Maximum reservoir of blood:
a. Veins
b. Aorta
c. Heart
d. Capillaries
Answer: a. Veins
Description:The maximum reservoir of blood in the body is actually found in the (c) Heart. The heart serves as a pump that continuously receives blood from the veins and propels it into the arteries, supplying oxygen and nutrients to the body's tissues. While veins do contain a significant amount of blood, the heart is responsible for storing and circulating the largest amount of blood in the cardiovascular system.
8. Biconcave shape of RBC’s is helpful because
a. Easily passages through capillaries.
b. Increased surface area for a given diameter.
c. Both a and b
d. None of the above
Answer: c. Both a and b
Description:The biconcave shape of red blood cells (RBCs) is helpful for several reasons: a. Easily passages through capillaries: The biconcave shape allows RBCs to be flexible and deformable, enabling them to squeeze through narrow capillaries and small blood vessels. This shape helps RBCs navigate through the intricate network of capillaries in various tissues and organs, ensuring efficient oxygen and nutrient delivery. b. Increased surface area for a given diameter: The biconcave shape maximizes the surface area-to-volume ratio of RBCs. This increased surface area enhances the exchange of oxygen and carbon dioxide across the RBC membrane. It allows for more efficient diffusion of these gases, as well as other nutrients and waste products, between the RBCs and the surrounding tissues. Therefore, the biconcave shape of RBCs is beneficial because it enables them to easily pass through capillaries and provides an increased surface area for a given diameter, allowing for efficient gas exchange.
9. The largest group of axillary lymph nodes is:
a. Central
b. Lateral
c. Apical
d. Media
Answer: a. Central
Description:The axillary lymph nodes are a group of lymph nodes located in the axilla, or armpit. They play a crucial role in the immune system and are responsible for draining lymphatic fluid from the upper limb, breast, and surrounding areas. There are several groups of axillary lymph nodes, including the central, lateral, apical, anterior, and posterior groups. Among these, the apical group is the largest. The apical lymph nodes, also known as the subclavicular lymph nodes or the infraclavicular lymph nodes, are located at the apex or uppermost part of the axilla, near the clavicle. These apical lymph nodes receive lymphatic drainage from the other axillary lymph node groups and are responsible for draining lymph from the upper limb, upper chest wall, and breast.
10. Brach of science that studies the disease of blood and approach to their diagnosis is:
a. Hematopathology
b. Forensic pathology
c. Transfusion medicine
d. Clinical pathology
Answer: a. Hematopathology
Description:Hematopathology is a branch of science that focuses on the study and diagnosis of diseases related to blood and bone marrow. It involves the examination of blood cells, bone marrow, and lymphoid tissues to identify and classify various blood disorders, including leukemia, lymphoma, anemia, and other hematological malignancies. Hematopathologists, who specialize in this field, analyze blood samples, perform bone marrow biopsies, and interpret the findings to make accurate diagnoses. They use various laboratory techniques, such as blood cell morphology, flow cytometry, immunohistochemistry, and molecular genetics, to study and classify blood diseases. Forensic pathology, on the other hand, deals with the investigation of sudden and unexpected deaths, including determining the cause and manner of death. It is not specifically focused on the study of blood diseases. Transfusion medicine primarily focuses on the safe and effective use of blood and blood products for transfusion purposes, including blood typing, compatibility testing, and monitoring transfusion reactions. Clinical pathology is a broad field that encompasses the laboratory analysis of bodily fluids and tissues to aid in the diagnosis and management of diseases. It includes various sub-disciplines, such as hematology, clinical chemistry, microbiology, and immunology. While hematology within clinical pathology deals with blood disorders, hematopathology specifically specializes in the study and diagnosis of blood diseases.
11. Which among the following suggests problem with hematological system?
a. Jaundice
b. Asthma
c. Renal Calculi
d. None of these
Answer: a. Jaundice
Description:If there is any problem with hematological system, increased RBC break down can occur and pigment will be released into the blood stream and can lead to jaundice. Asthma and renal calculi are unrelated to hematological system.
12. Blood coagulation requires:
a. Vit. K
b. Calcium
c. Fibrinogen
d. All of these
Answer: d. All of these
Description:Blood coagulation, also known as clotting, is a complex process that involves multiple factors. The process of blood clotting requires the following: a. Vitamin K: Vitamin K plays a crucial role in the production of several clotting factors, including factors II, VII, IX, and X. These factors are important for the formation of a stable blood clot. b. Calcium: Calcium ions are essential for the activation of various clotting factors. Calcium ions help convert inactive clotting factors into their active forms, enabling the formation of a blood clot. c. Fibrinogen: Fibrinogen is a soluble protein present in the blood plasma. During clotting, fibrinogen is converted into insoluble fibrin strands, which form a mesh-like network that traps blood cells and platelets, forming a blood clot.
13. Vitamin required for maintaining blood circulation and coagulation is:
a. Vit. A
b. Vit. D
c. Vit. E
d. Vit. K
Answer: d. Vit. K
Description:Vitamin K is essential for maintaining blood circulation and coagulation. It plays a crucial role in the synthesis of clotting factors in the liver, which are necessary for blood to clot properly. Without sufficient vitamin K, blood clotting may be impaired, leading to excessive bleeding or easy bruising. While vitamins A, D, and E are important for various bodily functions, they are not directly involved in blood circulation and coagulation. Vitamin A is involved in vision and immune function, vitamin D is important for bone health and calcium absorption, and vitamin E is an antioxidant that helps protect cells from damage. It's important to note that a balanced diet that includes a variety of nutrient-rich foods is the best way to ensure you are getting all the necessary vitamins and minerals, including vitamin K, for maintaining overall health and well-being.
14. Macrophages are responsible for:
a. Phagocytosis
b. Pinocytosis
c. Apoptosis
d. Endocytosis
Answer: a. Phagocytosis
Description:Macrophages are responsible for phagocytosis. Phagocytosis is the process by which cells engulf and digest foreign particles, such as bacteria, dead cells, and cellular debris. Macrophages are a type of white blood cell and are part of the immune system. They play a crucial role in the body's defense against pathogens and foreign substances by recognizing, engulfing, and destroying them through phagocytosis.
15. Neutrophils are responsible for:
a. Apoptosis
b. Pinocytosis
c. Phagocytosis
d. Endocytosis
Answer: c. Phagocytosis
Description: Neutrophils are primarily responsible for phagocytosis, which is the process of engulfing and destroying invading microorganisms, such as bacteria, fungi, and other foreign particles. Neutrophils are a type of white blood cell and are an essential component of the immune system's innate response to infection and inflammation. They are highly mobile and are among the first immune cells to arrive at the site of infection.
16. The last product in the process of blood coagulation is:
a. Thromboplastin
b. Prothrombin
c. Fibrin
d. Thrombin
Answer: c. Fibrin
Description:The last product in the process of blood coagulation is d. Thrombin. Thrombin is an enzyme that is formed from its precursor, prothrombin, through a series of reactions involving various clotting factors. Thrombin plays a crucial role in the clotting cascade by converting soluble fibrinogen into insoluble fibrin strands. These fibrin strands form a meshwork that helps to stabilize the blood clot and stop bleeding.
17. Leukocytes consists of all; EXCEPT:
a. Neutrophils
b. Eosinophil
c. Basophil
d. Thrombocytes
Answer: d. Thrombocytes
Description:Leukocytes, also known as white blood cells, are a crucial part of the immune system. They help defend the body against infections and foreign substances. The different types of leukocytes include neutrophils, eosinophils, and basophils. Thrombocytes, on the other hand, are not leukocytes. They are actually platelets, which are involved in blood clotting.
18. Granulocytes are:
a. Neutrophil
b. Eosinophil
c. Basophil
d. All of these
Answer: d. All of these
Description:Granulocytes refer to a group of white blood cells that contain granules in their cytoplasm. These granulocytes include neutrophils, eosinophils, and basophils.
19. Agranulocyte is/are:
a. Neutrophil
b. Monocyte
c. Lymphocyte
d. Both b and c
Answer: d. Both b and c
Description:The agranulocytes refer to a category of white blood cells that do not possess granules in their cytoplasm. The correct answer is d) Both b and c. Monocytes and lymphocytes are agranulocytes. Monocytes are large cells with a kidney-shaped nucleus, and they play a role in immune responses by phagocytizing foreign particles and presenting antigens to other immune cells. Lymphocytes are responsible for specific immune responses, including the production of antibodies and the recognition of specific antigens. They can be further categorized into B cells, T cells, and natural killer (NK) cells.
20. All statements are correct regarding lymphocytes; EXCEPT:
a. Comprise 25-40% of white cell population.
b. Small and large types can be seen
c. It belongs to agranulocyte.
d. T lymphocytes mature in Thyroid gland.
Answer: d. T lymphocytes mature in Thyroid gland.
Description:T lymphocytes, also known as T cells, mature in the thymus gland, not the thyroid gland. The thymus is a specialized organ of the immune system located in the upper chest region behind the sternum. T lymphocytes undergo maturation and selection processes in the thymus before they are released into circulation
21. All are true regarding monocytes; EXCEPT:
a. Largest leukocytes can be seen
b. Abundant blue gray cytoplasm
c. Perform phagocytic action
d. It belongs to granulocyte category
Answer: d. It belongs to granulocyte category
Description:Monocytes do not belong to the granulocyte category. Monocytes are a type of white blood cell, but unlike granulocytes (such as neutrophils, eosinophils, and basophils), monocytes do not contain granules in their cytoplasm. Monocytes have a large nucleus and abundant blue-gray cytoplasm. They are known for their phagocytic action, which involves engulfing and digesting foreign particles, dead cells, and cellular debris. Monocytes are the largest leukocytes that can be seen in the blood.
22. Identify correct statement regarding Eosinophil:
a. 1-6% of total leukocyte count
b. Larger than neutrophils
c. Count will elevate during allergic reaction
d. All of these
Answer: d. All of these
Description:Eosinophils typically make up 1-6% of the total leukocyte count in the blood. They are slightly larger than neutrophils. Additionally, the count of eosinophils tends to elevate during allergic reactions, parasitic infections, and certain other conditions. Therefore, all of the statements (a, b, and c) are correct.
23. Which among the following is required for the production of RBCs?
a. Vitamin A
b. Folic acid
c. Vitamin D
d. Vitamin E
Answer: b. Folic acid
Description:Among the options provided, folic acid is required for the production of red blood cells (RBCs). Folic acid, also known as vitamin B9, is an essential nutrient that plays a crucial role in DNA synthesis and cell division. It is particularly important for the rapid cell growth and division that occurs during the production of RBCs in the bone marrow. Folic acid deficiency can lead to a condition called megaloblastic anemia, characterized by abnormally large and immature RBCs. Adequate intake of folic acid is necessary to support RBC production and maintain healthy blood levels.
24. What is the function of thymus gland?
a. Store melanin
b. Store blood cells until they mature
c. Maintain circadian rhythm
d. Kill pathogens
Answer: b. Store blood cells until they mature
Description:The thymus gland is a small organ located in the upper chest, behind the breastbone. Its primary function is to facilitate the maturation and development of specific immune cells called T lymphocytes or T cells. T cells play a crucial role in the immune system's defense against pathogens, such as bacteria, viruses, and other foreign substances. During early life, the thymus gland is particularly active and produces large numbers of T cells. These T cells then migrate to other organs in the body, such as the lymph nodes and spleen, where they continue to mature and become fully functional. The thymus gland also helps in the selection and elimination of T cells that may recognize and attack the body's own cells, preventing autoimmune reactions. It is worth mentioning that the other options you provided (a. Store melanin, c. Maintain circadian rhythm, and d. Kill pathogens) are not functions of the thymus gland.
25. True about macrophage is:
a. Macrophages are found in Late phase of inflammation.
b. Histocytes, Kupffer cells, Osteoclasts are the example of macrophages.
c. Both a and b
d. None of the above
Answer: c. Both a and b
Description:a. Macrophages are indeed found in the late phase of inflammation. During inflammation, macrophages are recruited to the site of injury or infection and play a crucial role in resolving inflammation and promoting tissue repair. b. Histocytes, Kupffer cells, and osteoclasts are all examples of macrophages. Histocytes are macrophages found in connective tissue, Kupffer cells are macrophages found in the liver, and osteoclasts are macrophages involved in bone remodeling.
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