NATIONAL AND STATE NURSING EXAM- MCQ _MG_00103
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1. Fasting blood sugar is 120 mg/dL and 2 h post prandial sugar after 75 g of oral glucose administration is 180 mg/dL diagnosis is:
a. Normal individual
b. Impaired glucose tolerance
c. Pre-diabetes
d. Diabetes mellitus
Answer: c. Pre-diabetes
Description:A fasting blood sugar level of 120 mg/dL and a 2-hour post-prandial sugar level of 180 mg/dL are both within the pre-diabetes range. Pre-diabetes is a condition in which blood sugar levels are higher than normal but not high enough to be diagnosed as diabetes. If you have pre-diabetes, you are at an increased risk of developing diabetes. However, there are things you can do to reduce your risk, such as: Eating a healthy diet Exercising regularly Losing weight, if you are overweight or obese Taking medication, if necessary If you have pre-diabetes, it is important to work with your doctor to develop a treatment plan that will help you prevent diabetes. The other options are incorrect. A normal fasting blood sugar level is less than 100 mg/dL. Impaired glucose tolerance is a condition in which blood sugar levels are higher than normal after a meal but not high enough to be diagnosed as diabetes. Diabetes mellitus is a condition in which blood sugar levels are consistently high.
2. In a person with hypocalcemia parathyroid dysfunction is suspected, the confirmatory diagnosis test shows:
a. Decreased parathormone
b. Increased parathormone
c. Decreased calcitonin
d. Increased serum calcium
Answer: a. Decreased parathormone
Description:Hypocalcemia refers to a low level of calcium in the blood. Parathyroid dysfunction is one of the possible causes of hypocalcemia. The parathyroid glands are responsible for producing parathyroid hormone (PTH), which helps regulate calcium levels in the body. In a person with parathyroid dysfunction, such as hypoparathyroidism, the parathyroid glands do not produce enough PTH. As a result, the level of PTH in the blood is decreased. This decrease in PTH can lead to lower levels of calcium in the blood, causing hypocalcemia. Confirmatory diagnostic tests for parathyroid dysfunction may involve measuring the levels of PTH in the blood. If the person has hypocalcemia due to parathyroid dysfunction, the test would typically show decreased levels of parathormone (PTH). Therefore, option a. Decreased parathormone is the correct answer indicating parathyroid dysfunction in a person with hypocalcemia.
3. Diagnostic test specific to Cushing syndrome is:
a. Urine cortisol level
b. Dexamethasone suppression test
c. Plasma cortisol level
d. All of these
Answer: d. All of these
Description:Cushing syndrome is a condition that occurs when the body produces too much cortisol. Cortisol is a hormone that is produced by the adrenal glands. There are a number of diagnostic tests that can be used to diagnose Cushing syndrome, including: Urine cortisol level: This test measures the amount of cortisol in the urine. A high urine cortisol level is a sign of Cushing syndrome. Dexamethasone suppression test: This test is used to measure how well the body responds to dexamethasone. Dexamethasone is a synthetic cortisol that suppresses the production of cortisol by the adrenal glands. If the body does not respond to dexamethasone, it is a sign of Cushing syndrome. Plasma cortisol level: This test measures the amount of cortisol in the blood. A high plasma cortisol level is a sign of Cushing syndrome. The combination of these tests can be used to diagnose Cushing syndrome with a high degree of accuracy. The other options are incorrect. A single test is not enough to diagnose Cushing syndrome. A combination of tests is needed to make a definitive diagnosis.
4. Levodopa test in used to detect:
a. LH
b. ACTH
c. FSH
d. GH reserve
Answer: d. GH reserve
Description:The levodopa test, also known as the L-dopa stimulation test, is used to assess growth hormone (GH) reserve or function. It is a diagnostic test that helps determine if the body is able to produce adequate amounts of GH in response to stimulation. During the levodopa test, the individual is given a dose of levodopa, which is a precursor of dopamine. Dopamine acts as a stimulant for the release of GH from the pituitary gland. In a normal response, the levodopa stimulates the pituitary gland to release GH, leading to an increase in GH levels in the blood. By measuring GH levels before and after the administration of levodopa, doctors can evaluate the GH reserve and determine if there is an underlying deficiency or dysfunction in the production of GH. This test is commonly used to diagnose growth hormone deficiencies and disorders.
5. Most sensitive method to diagnosis thyroid function is:
a. T3
b. T4
c. TSH
d. Thyroglobulin
Answer: c. TSH
Description:• Most sensitive and specific test to detect hypothyroidism and hypothyroidism is TSH assay • Total T4: Reflects output from thyroid gland • Total T3: More indicative of peripheral thyroid metabolism, hence, not useful for screening.
6. Gigantism is seen in:
a. Hyperpituitarism
b. Hypopituitarism
c. Hyperthyroidism
d. Hypothyroidism
Answer: a. Hyperpituitarism
Description:Gigantism is a rare condition that occurs when a child's pituitary gland produces too much growth hormone. This causes the child to grow taller than normal. Gigantism is typically caused by a benign tumor on the pituitary gland. Hypopituitarism is a condition that occurs when the pituitary gland does not produce enough hormones. This can cause a number of problems, including growth problems, infertility, and fatigue. Hyperthyroidism is a condition that occurs when the thyroid gland produces too much thyroid hormone. This can cause a number of problems, including weight loss, anxiety, and heat intolerance. Hypothyroidism is a condition that occurs when the thyroid gland does not produce enough thyroid hormone. This can cause a number of problems, including weight gain, fatigue, and cold intolerance. So, gigantism is seen in hyperpituitarism, not hypopituitarism, hyperthyroidism, or hypothyroidism.
7. Short stature, secondary to growth hormone deficiency is associated with:
a. Height age is equal to Bone age
b. Normal body proportion
c. Low birth weight
d. Normal epiphyseal development
Answer: b. Normal body proportion
Description:Growth Hormone deficiency:
• GHD babies are born AGA (not SGA)
• They have maintained body proportions. i.e., proportionate short stature
• Disproportionate SS is seen in following (Upper segment: lower segment)
• US>LS →Richest and achondroplasia
• US
8. The hyper secretion of growth hormone leads to:
a. Cretinism
b. Myxedema
c. Acromegaly
d. Grave’s disease
Answer: c. Acromegaly
Description:Acromegaly is a condition that occurs due to the excessive secretion of growth hormone (GH) by the pituitary gland in adulthood. It is typically caused by a noncancerous tumor of the pituitary gland called a pituitary adenoma. When there is hypersecretion of GH, it leads to increased production of insulin-like growth factor 1 (IGF-1) in the liver and other tissues. Excess GH and IGF-1 cause abnormal growth and enlargement of tissues and organs in the body, particularly in the hands, feet, face, and internal organs. Common features of acromegaly include enlarged hands and feet, facial changes such as a protruding jaw or enlarged nose, thickened skin, enlarged organs, and joint problems. Cretinism refers to a condition of severe congenital hypothyroidism, characterized by stunted growth and intellectual disability. Myxedema is a term used to describe the severe form of hypothyroidism in adults, which is characterized by a general slowing of mental and physical activity. Grave's disease is an autoimmune disorder that results in overactivity of the thyroid gland, leading to hyperthyroidism. Therefore, option c. Acromegaly is the correct answer for the condition associated with the hypersecretion of growth hormone.
9. Excessive secretion of growth hormone by anterior pituitary in prepubertal children causes:
a. Addison’s disease
b. Cushing’s disease
c. Gigantism
d. Adenomegaly
Answer: c. Gigantism
Description:Gigantism is a condition that occurs when a child's pituitary gland produces too much growth hormone. This causes the child to grow taller than normal. Gigantism is typically caused by a benign tumor on the pituitary gland. Addison's disease is a condition that occurs when the adrenal glands do not produce enough cortisol. Cortisol is a hormone that helps the body respond to stress. Cushing's disease is a condition that occurs when the body produces too much cortisol. Cortisol is a hormone that helps the body respond to stress. Adenomegaly is a condition that occurs when an endocrine gland becomes enlarged. So, excessive secretion of growth hormone by anterior pituitary in prepubertal children causes gigantism, not Addison's disease, Cushing's disease, or adenomegaly.
10. Lack of thyroid hormone in children leads to:
a. Cretinism
b. Gigantism
c. Acromegaly
d. Grave’s disease
Answer: a. Cretinism
Description:Cretinism refers to a condition of severe congenital hypothyroidism, which is a lack of thyroid hormone in children from birth or early infancy. Thyroid hormone plays a crucial role in the growth and development of children, particularly in the development of the brain and skeletal system. When there is a deficiency of thyroid hormone, it can lead to impaired physical and mental growth. Children with cretinism typically exhibit stunted growth, both in terms of height and overall development. They may also have intellectual disabilities, delayed puberty, delayed skeletal maturation, and characteristic facial features such as a puffy face, a large tongue, and a broad nose. Gigantism refers to excessive growth and height in children due to an overproduction of growth hormone before the fusion of the growth plates. Acromegaly, as mentioned earlier, is the condition of excessive growth hormone secretion in adults, leading to abnormal growth of tissues and organs. Grave's disease is an autoimmune disorder that results in overactivity of the thyroid gland, leading to hyperthyroidism. Therefore, option a. Cretinism is the correct answer for the condition associated with a lack of thyroid hormone in children.
11. Which of the following is the most common causes of hypopituitarism?
a. Congenital adenoma
b. Pituitary adenoma
c. Craniopharyngioma
d. None of the above
Answer: b. Pituitary adenoma
Description:Pituitary adenomas are the most common cause of hypopituitarism in adults. They are benign tumors that grow on the pituitary gland. These tumors can damage the pituitary gland and prevent it from producing enough hormones. Congenital adenoma is a rare condition that occurs when a person is born with a pituitary gland that does not function properly. Craniopharyngioma is a tumor that grows in the brain near the pituitary gland. It can also damage the pituitary gland and cause hypopituitarism. So, the most common cause of hypopituitarism is pituitary adenoma
12. Panhypopituitarism is also called:
a. Simmonds’s disease
b. Sheehan’s syndrome
c. Kahler’s disease
d. Basdeo’s disease
Answer: a. Simmonds’s disease
Description:Panhypopituitarism is a condition characterized by the deficiency or absence of hormone production by the pituitary gland, which is located at the base of the brain. It is also referred to as Simmonds's disease, named after the British physician Sir Edward Albert Sharpey-Schafer Simmonds. In panhypopituitarism, the pituitary gland fails to produce adequate levels of multiple hormones, including growth hormone (GH), thyroid-stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), luteinizing hormone (LH), follicle-stimulating hormone (FSH), prolactin, and antidiuretic hormone (ADH). This deficiency of hormones can lead to a wide range of symptoms and complications depending on which hormones are affected. Sheehan's syndrome, option b, is a condition that occurs due to postpartum pituitary necrosis caused by severe blood loss during childbirth. It specifically affects the production of hormones by the pituitary gland. Kahler's disease, option c, refers to multiple myeloma, a type of cancer affecting plasma cells in the bone marrow. It is unrelated to panhypopituitarism. Basdeo's disease, option d, does not correspond to a recognized medical condition. Therefore, the correct answer is a. Simmonds's disease for panhypopituitarism.
13. After a hypophysectomy procedure, which of the following statement by the client represents best understanding of the health education?
a. Thyroid hormone replacement therapy is the essential one
b. My menstruation will be ceased
c. I may had infertility
d. All of these
Answer: d. All of these
Description:Hypophysectomy is a surgical procedure that removes part or all of the pituitary gland. The pituitary gland is a small gland that is located at the base of the brain. It produces a number of hormones that are essential for many body functions, including growth, reproduction, and metabolism. After a hypophysectomy, the patient will need to take hormone replacement therapy for the rest of their life. The specific hormones that the patient will need to take will depend on the extent of the surgery and the hormones that the pituitary gland was producing before the surgery. In addition to hormone replacement therapy, the patient may also experience other changes after a hypophysectomy, such as: Cessation of menstruation Infertility Fatigue Weight gain Changes in skin and hair It is important for the patient to understand these changes so that they can manage them appropriately. The patient should also work with their doctor to develop a treatment plan that will help them to maintain their health after the surgery. The statement "Thyroid hormone replacement therapy is the essential one" is correct because the thyroid gland is one of the glands that is affected by hypophysectomy. The statement "My menstruation will be ceased" is also correct because the pituitary gland produces hormones that are essential for menstruation. The statement "I may had infertility" is also correct because the pituitary gland produces hormones that are essential for reproduction. So, the best statement that represents the client's understanding of the health education is "All of these."
14. The syndrome which commonly occur in women with severe blood loss at the time of delivery is called:
a. Sheehan’s disease
b. Cushing disease
c. Turner syndrome
d. Simmonds disease
Answer: a. Sheehan’s disease
Description:Sheehan’s syndrome (SS) is postpartum hypopituitarism caused by necrosis of the pituitary gland. It is usually the result of severe hypotension or shock caused by measure hemorrhage during or after delivery.
15. Increased blood sugar level is the characteristic feature of all of the following; EXCEPT:
a. Eosinophilic tumor
b. Basophilic tumor
c. Monophilic tumor
d. Chromophobic tumor
Answer: a. Eosinophilic tumor
Description:Increased blood sugar level, also known as hyperglycemia, is a characteristic feature of several conditions, including certain endocrine disorders. However, eosinophilic tumors do not typically cause increased blood sugar levels. Eosinophilic tumors, also known as eosinophilic adenomas or tumors, refer to tumors that contain eosinophilic cells. Eosinophils are a type of white blood cell involved in the immune response and are not directly associated with blood sugar regulation. On the other hand, basophilic tumors, monophilic tumors, and chromophobic tumors are terms that are not commonly used in medical literature. It is unclear what specific characteristics or conditions they may refer to. In summary, while increased blood sugar levels can be seen in various endocrine disorders, eosinophilic tumors do not typically cause such an effect. Therefore, option a. Eosinophilic tumor is the correct answer for the condition that does not exhibit increased blood sugar levels.
16. Priority nursing management in a client with diabetes insipidus is:
a. Hourly urine output
b. Hourly blood glucose
c. Hourly head circumference
d. Hourly abdominal circumference
Answer: a. Hourly urine output
Description:In a client with diabetes insipidus (DI), the priority nursing management would involve monitoring and assessing the hourly urine output. Diabetes insipidus is characterized by excessive urine production (polyuria) due to the inability of the kidneys to properly concentrate urine. By closely monitoring the hourly urine output, the nurse can assess the effectiveness of treatment and the client's fluid balance. The goal is to ensure that the client's urine output is within a normal range and that they are not becoming dehydrated due to excessive fluid loss. Hourly blood glucose monitoring, option b, would not be the priority in diabetes insipidus since diabetes insipidus is not related to blood glucose regulation. Monitoring blood glucose levels is more relevant for conditions such as diabetes mellitus. Hourly head circumference monitoring, option c, and hourly abdominal circumference monitoring, option d, are not directly related to diabetes insipidus. These measurements may be more relevant in conditions affecting neurological or gastrointestinal systems, respectively. Therefore, option a. Hourly urine output is the priority nursing management in a client with diabetes insipidus.
17. Clinical manifestations of SIADH includes:
a. Increased urine Na+
b. Decreased serum Na+
c. Increased urine osmolality
d. All of these
Answer: d. All of these
Description:I apologize for the repetition in my previous response. You are correct, the correct answer is indeed d. All of these. Clinical manifestations of SIADH (syndrome of inappropriate antidiuretic hormone secretion) include: a. Increased urine Na+: SIADH leads to the excessive release of antidiuretic hormone (ADH), which causes the kidneys to retain water and concentrate urine. As a result, the concentration of sodium in the urine increases, leading to increased urine sodium (Na+) levels. b. Decreased serum Na+: The excessive retention of water caused by SIADH dilutes the concentration of sodium in the blood, resulting in decreased serum sodium (Na+) levels. This condition is known as hyponatremia. c. Increased urine osmolality: SIADH disrupts the normal balance of water and solute excretion in the kidneys. The excessive release of ADH leads to increased water reabsorption, causing urine to become more concentrated. This results in increased urine osmolality, which reflects a higher concentration of solutes in the urine. Therefore, option d. All of these is the correct answer as all of these manifestations are observed in SIADH: increased urine Na+, decreased serum Na+, and increased urine osmolality.
18. Increased blood sugar level is the characteristic feature of all of the following; EXCEPT:
a. Diabetes mellitus
b. Corticosteroid therapy
c. Pancreatitis
d. SIADH
Answer: d. SIADH
Description:The answer is d) SIADH. SIADH, or Syndrome of Inappropriate Antidiuretic Hormone Secretion, is a condition in which the body produces too much of the hormone ADH. ADH is a hormone that helps the body retain water. When too much ADH is produced, the body retains too much water and the blood becomes too dilute. This can lead to a number of symptoms, including: Decreased serum sodium: This is the most common symptom of SIADH. The normal serum sodium level is 135-145 mEq/L. In SIADH, the serum sodium level can be as low as 110 mEq/L. Increased urine osmolality: This means that the urine is more concentrated than normal. The normal urine osmolality is 250-300 mOsm/kg. In SIADH, the urine osmolality can be as high as 800 mOsm/kg. Increased urine sodium: This means that the urine contains more sodium than normal. The normal urine sodium level is 20-40 mEq/L. In SIADH, the urine sodium level can be as high as 100 mEq/L. However, blood sugar levels are not typically elevated in SIADH. In fact, blood sugar levels may even be decreased in SIADH due to the dilution of the blood. The other options are all correct. Diabetes mellitus is a chronic condition that is characterized by high blood sugar levels. Corticosteroid therapy can also cause high blood sugar levels. Pancreatitis is an inflammation of the pancreas that can also cause high blood sugar levels. So, the only option that does not have increased blood sugar levels is SIADH
19. The hypofunction of the anterior pituitary gland that rarely affects the posterior lobe leading to:
a. Grave’s disease
b. Simmonds’s disease
c. Frohlick’s syndrome
d. Levi syndrome
Answer: b. Simmonds’s disease
Description:Simmonds's disease, also known as panhypopituitarism, is a rare condition that occurs when the anterior pituitary gland fails to produce any hormones. This can lead to a number of symptoms, including: Hypothyroidism Hypogonadism Growth hormone deficiency Adrenal insufficiency Diabetes insipidus Simmonds's disease is often caused by damage to the pituitary gland, such as from a tumor or an infection. It can also be caused by a congenital defect. The treatment for Simmonds's disease depends on the underlying cause. In some cases, the cause of Simmonds's disease can be treated, which will resolve the symptoms. In other cases, the treatment will focus on managing the symptoms. Treatment options may include: Hormone replacement therapy: This means taking hormones that the pituitary gland is no longer able to produce. Lifestyle changes: These may include changes in diet, exercise, and stress management. With treatment, most people with Simmonds's disease can live normal lives. The other options are incorrect. Grave's disease is an autoimmune disorder that causes hyperthyroidism. Frohlick's syndrome is a condition that is characterized by high levels of growth hormone. Levi syndrome is a condition that is characterized by low levels of growth hormone.
20. Twelve hours after a transsphenoidal hypophysectomy, the client keeps clearing his throat and complains of a drip in his mouth. To accurately asses this, the nurse should test the fluid for:
a. Glucose
b. Protein
c. Bacteria
d. Blood
Answer: a. Glucose
Description:Dripping in the back of the throat after a transsphenoidal hypophysectomy may be cerebrospinal fluid. CSF contains glucose. Testing for glucose will confirm if CSF present in the fluid. Saliva and mucus do not contain glucose.
21. Diabetes insipidus is caused by the deficiency of:
a. Antidiuretic hormone
b. Insulin
c. Glucagon
d. Renin
Answer: a. Antidiuretic hormone
Description:Diabetes insipidus (DI) is a condition caused by inadequate output of the pituitary hormone ADH (Antidiuretic hormone). It is characterized by excessive thirst and excretion of large amounts of diluted urine.
22. Clinical manifestations expected in a client with diabetes insipidus is:
a. Polyuria and hyponatremia
b. Polyuria and hypernatremia
c. Low urine output and hyponatremia
d. Low urine output and hypernatremia
Answer: b. Polyuria and hypernatremia
Description:Diabetes insipidus (DI) is a condition characterized by the inability of the kidneys to properly concentrate urine, leading to excessive urine production (polyuria) and increased thirst (polydipsia). It is caused by a deficiency or dysfunction of antidiuretic hormone (ADH), also known as vasopressin. Due to the lack of ADH, the kidneys are unable to reabsorb water properly, resulting in the excretion of large volumes of dilute urine. This leads to polyuria, which is a hallmark symptom of diabetes insipidus. In addition to polyuria, another important manifestation of diabetes insipidus is hypernatremia. Hypernatremia refers to an elevated level of sodium in the blood. Since excessive water is being excreted in the urine, there is a relative loss of water compared to sodium in the body, causing sodium concentration to increase. Therefore, option b. Polyuria and hypernatremia is the correct answer for the clinical manifestations expected in a client with diabetes insipidus.
23. In a client with diabetes insipidus, the serum sodium level:
a. Increases
b. Decreases
c. With the normal range
d. Fluctuating
Answer: a. Increases
Description:Diabetes insipidus is a condition in which the body does not produce enough of the hormone ADH. ADH is a hormone that helps the body retain water. When too little ADH is produced, the body loses too much water and the blood becomes concentrated. This can lead to a number of symptoms, including: Increased thirst Frequent urination Decreased urine osmolality Increased serum sodium level The serum sodium level in a client with diabetes insipidus will typically increase due to the loss of water. The normal serum sodium level is 135-145 mEq/L. In diabetes insipidus, the serum sodium level can be as high as 155 mEq/L. The other options are incorrect. The serum sodium level does not typically decrease in diabetes insipidus. The serum sodium level may be within the normal range in mild cases of diabetes insipidus. The serum sodium level may fluctuate in some cases of diabetes insipidus, but it will typically be elevated.
24. Water derivate test is used for the diagnosis of:
a. Diabetic mellitus
b. Diabetic insipidus
c. SIADH
d. Diabetic ketoacidosis
Answer: b. Diabetic insipidus
Description:In diabetic insipidus water intake will be restricted in the person, following that, if urine output increase and weight loss occurs in a person, then the person is diagnosed as diabetes insipidus
25. Causes of nephrogenic diabetes insipidus include:
a. Idiopathic
b. Genetic
c. Head injury
d. Histiocytosis
Answer: b. Genetic
Description:Nephrogenic diabetes insipidus (NDI) is characterized by inability to concentrate the urine, which results in polyuria (excess urine production) and polydipsia. Cause of nephrogenic diabetes insipidus is either acquired or hereditary (generic). Options a, c, and d are causes of cranial diabetes insipidus. Genetic is the most common cause for nephrogenic diabetes insipidus
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