NATIONAL AND STATE NURSING EXAM- MCQ _MG_00 194
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1. Which among the following penicillin has the longest duration of action?
a. Benthamite penicillin
b. Benzathine penicillin
c. Potassium pheneticillin
d. Procaine penicillin - G
Answer: b. Benzathine penicillin
Description:Among the options provided, benzathine penicillin (option b) typically has the longest duration of action. It is a long-acting penicillin that is slowly absorbed into the bloodstream, leading to a prolonged therapeutic effect. This property makes it suitable for treating certain infections that require a sustained release of penicillin over an extended period.
2. Which of the following is not a natural penicillin?
a. Ampicillin
b. Procaine penicillin – G
c. Benzyl penicillin -G
d. Benzathine penicillin
Answer: a. Ampicillin
Description:Ampicillin, is not a natural penicillin. Ampicillin is a semi-synthetic penicillin, which means it is derived from natural penicillin but has been chemically modified to enhance its spectrum of activity and improve its stability. Natural penicillins include benzylpenicillin (penicillin G), procaine penicillin G, and benzathine penicillin, while ampicillin falls into the category of semi-synthetic penicillin's.
3. Which of the following antimicrobial agent is most useful in the treatment of amoebic dysentery?
a. Cefotaxime
b. Ofloxacin
c. Metronidazole
d. Ciprofloxacin
Answer: c. Metronidazole
Description:The most useful antimicrobial agent for the treatment of amoebic dysentery is metronidazole (option c). Metronidazole is an antibiotic specifically effective against anaerobic bacteria and parasites, including the amoeba Entamoeba histolytica, which causes amoebic dysentery. Cefotaxime (option a), ciprofloxacin (option b), and ofloxacin (option d) are not typically used as first-line treatments for amoebic dysentery.
4. Drugs useful against bacteria resistant to penicillin include:
a. Erythromycins
b. Amoxicillin
c. Cephalosporin
d. Both a and b
Answer: d. Both a and b
Description:Cephalosporins (option a) and erythromycins (option b) are both antibiotics that are effective against bacteria resistant to penicillin. They belong to different antibiotic classes and have different mechanisms of action, making them valuable alternatives when penicillin resistance is encountered. Amoxicillin (option c) is a penicillin-type antibiotic and would not be considered effective against bacteria that are resistant to penicillin.
5. Anticipatory nausea and vomiting occurs:
a. During chemotherapy administration
b. Before chemotherapy administration
c. Within the few hours after chemotherapy.
d. One week after chemotherapy
Answer: b. Before chemotherapy administration
Description:Anticipatory nausea and vomiting associated with chemotherapy occurs prior to administration of chemotherapy.
6. Ondansetron administered before chemotherapy is to prevent:
a. Anemia
b. Alopecia
c. Pain
d. Vomiting
Answer: d. Vomiting
Description:Ondansetron is an antiemetic agent which prevents nausea and vomiting.
7. Methotrexate acts by inhibition of:
a. Sterol synthesis
b. Aldose dehydrogenase
c. Dihydrofolate reductase
d. Aldehyde dehydrogenase
Answer: c. Dihydrofolate reductase
Description:Methotrexate acts by inhibition of folate metabolism, blocking dihydrofolic acid reductase, thereby inhibiting synthesis of purines and pyrimidines and decreasing DNA and RNA synthesis.
8. Which of the following anticancer drug causes ‘Hand and foot syndrome’ as a side effect?
a. Vinblastine
b. Methotrexate
c. Capecitabine
d. Vincristine
Answer: c. Capecitabine
Description:One of the side effects of treatment with capecitabine in hand-foot syndrome.
9. Anticancer drug of plant sources
a. Vincristine
b. Bleomycin
c. Isotretinoin
d. Methotrexate
Answer: a. Vincristine
Description:Vincristine is an anticancer drug derived from the periwinkle plant (Vinca rosea). It is commonly used in the treatment of various types of cancer, including leukemia, lymphoma, and solid tumors. Vincristine belongs to a class of drugs known as vinca alkaloids, which are obtained from the Madagascar periwinkle plant and have demonstrated anticancer properties. Isotretinoin (option b), bleomycin (option c), and methotrexate (option d) are also used in cancer treatment, but they are not derived from plant sources.
10. What is the effect of cyclosporine in a patient undergone renal transplantation?
a. Immunosuppressant
b. Diuretic
c. Antibacterial
d. Anti-inflammatory
Answer: a. Immunosuppressant
Description:Cyclosporine is an immunosuppressant medication commonly used in patients who have undergone renal transplantation. It helps suppress the patient's immune system to prevent rejection of the transplanted kidney by inhibiting the activation of T lymphocytes (T cells), which play a key role in the immune response. This allows the transplanted kidney to function properly without being attacked by the recipient's immune system.
11. Which of the following solution is used as an antimicrobial cleanser to clean the skin site before surgery?
a. Chlorhexidine 0.5%
b. Glutaraldehyde >2%
c. Hydrogen peroxide 7.5%
d. Hypochlorite 650-675 ppm
Answer: a. Chlorhexidine 0.5%
Description:Glutaraldehyde (≥2.0%), hydrogen peroxide (7.5%) and hypochlorite (650-675 ppm) are high level disinfectant used for disinfection of surfaces and equipment/instruments. Chlorhexidine 0.5% is used as an antimicrobial cleanser to prepare the skin site before surgery in order to prevent surgical site infection.
12. Which of the following is used on live tissues to prevent infection?
a. Disinfectant
b. Antiseptic
c. Lotion
d. Sterile water
Answer: b. Antiseptic
Description:Antiseptics are used on live tissues to prevent infection. They are substances that are applied to living tissues (such as the skin or mucous membranes) to inhibit or kill microorganisms like bacteria, viruses, and fungi, thereby reducing the risk of infection. Disinfectants (option a) are typically used on inanimate objects and surfaces to kill or inhibit the growth of microorganisms. Lotion (option c) and sterile water (option d) are not specifically used for preventing infection; they serve different purposes.
13. Which of the following category of drug prevents the growth of molds and yeasts?
a. Bacteriostatic
b. Fungistatic
c. Fungicidal
d. Antiprotozoal
Answer: b. Fungistatic
Description:Fungistatic drugs are substances that prevent the growth of molds and yeasts, but they do not necessarily kill them. These drugs inhibit the replication and reproduction of fungal cells, which helps control fungal infections. Fungicidal drugs (option c), on the other hand, kill fungal cells outright. Bacteriostatic drugs (option a) prevent the growth of bacteria, and antiprotozoal drugs (option d) target protozoa, not molds and yeasts.
14. Iodophors belongs to which of the following chemical family?
a. Halogens
b. Aldehydes
c. Phenols
d. Ammonium compounds
Answer: a. Halogens
Description:Iodophors are combinations of iodine with surface active agents such as non-ionic detergents. They are non-staining and non-irritant, and are effective as antiseptics and as surface disinfectants.
15. The duration required for alcohol to be in wet contact with an item to achieve disinfection is:
a. 30 seconds
b. 1-2 m
c. 2-3 m
d. 5-10 m
Answer: d. 5-10 m
Description:Alcohol typically needs to be in wet contact with an item for 5-10 minutes to achieve disinfection. This duration allows the alcohol to effectively kill or inhibit the growth of microorganisms on the surface being treated.
16. Lansoprazole is not used in which of the following cases?
c. Zollinger-Ellison syndrome
a. Gastritis
b. Peptic ulcers
d. Thalamus hypertrophy
Answer: d. Thalamus hypertrophy
Description:• Lansoprazole is a proton pump inhibitor (PPI). In inhibits gastric acid secretion from the stomach. PPIs are used to treat peptic ulcer disease, gastroesophageal reflux disease (GERD), stress ulcers, Zollinger-Ellison syndrome (ZES) and aspiration pneumonia. • Dose: 15 mg and 30 mg.
17. Which of the following food enhances the absorption of an iron supplement?
a. Baked potato
b. Orange juice
c. Green beans
d. Fortified milk
Answer: b. Orange juice
Description:Orange juice is known to enhance the absorption of iron supplements. It contains vitamin C, which can significantly improve the absorption of non-heme iron (the type of iron found in plant-based foods and iron supplements) when consumed together. This is why it's often recommended to take iron supplements with vitamin C-rich foods or beverages like orange juice to increase iron absorption.
18. Which of the following drug is an example of proton pump inhibitor?
a. Pantoprazole
b. Famotidine
c. Ranitidine
d. Sucralfate
Answer: a. Pantoprazole
Description:Pantoprazole and omeprazole are proton pump inhibitors (PPI) which inhibits the production of hydrochloric acid in the stomach.
19. The drug used for prevention and treatment of nausea and vomiting is known as:
a. Antitussives
b. Antibiotics
c. Antiemetics
d. Antipyretics
Answer: c. Antiemetics
Description:An antiemetic is a drug that is effective against vomiting and nausea. Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics, general anesthetics and chemotherapy directed against cancer.
20. The drug used in the treatment of hook worm infestation is:
a. Albendazole
b. Bephenium hydroxynaphthoate
c. Mebendazole
d. Piperazine citrate.
Answer: a. Albendazole
Description:Albendazole is a drug commonly used in the treatment of hookworm infestations. It is effective against a variety of intestinal parasites, including hookworms. Bephenium hydroxynaphthoate (option b), mebendazole (option c), and piperazine citrate (option d) are also anthelmintic medications used to treat different types of intestinal worms, but albendazole is often preferred for hookworm infections.
21. Misoprostol, a prostaglandin analogue is useful as:
a. Uterine relaxant
b. Antiulcer
c. Bronchodilator
d. Vasodilator
Answer: b. Antiulcer
Description:Misoprostol is a prostaglandin analogue that is primarily used as an antiulcer medication. It helps protect the stomach lining by reducing the risk of ulcers caused by certain medications, particularly nonsteroidal anti-inflammatory drugs (NSAIDs). Misoprostol promotes the production of mucus in the stomach and reduces stomach acid secretion, which can help prevent or heal ulcers. It is not used as a uterine relaxant, bronchodilator, or vasodilator.
22. Drugs used to prevent or relieve nausea and vomiting are known as:
a. Antacids
b. Antiemetics
c. Antitussives
d. Emetics
Answer: b. Antiemetics
Description:Drugs used to prevent or relieve nausea and vomiting are known as antiemetics. These medications are commonly used to treat various conditions that can cause nausea and vomiting, such as motion sickness, chemotherapy-induced nausea, and postoperative nausea. Antacids (option a) are used to neutralize stomach acid, antitussives (option c) are used to suppress coughing, and emetics (option d) are used to induce vomiting, which is the opposite of what antiemetics do
23. Drugs used in the treatment of worm infestations are known as:
a. Antibiotics
b. Anthelmintics
c. Antimicrobials
d. Antiprotozoal
Answer: b. Anthelmintics
Description:Drugs used in the treatment of worm infestations are known as anthelmintics. Anthelmintics are medications specifically designed to treat infections caused by parasitic worms, including intestinal worms and other types of helminths. Antibiotics (option a) are used to treat bacterial infections, antimicrobials (option c) include a broader category of drugs used against various microorganisms, and antiprotozoal drugs (option d) are used to treat protozoal infections, not worm infestations.
24. Out of the following, which medicines are used for intestinal evacuation?
a. Cathartics
b. Carminatives
c. Astringents
d. Antiprotozoal
Answer: a. Cathartics
Description:Medications used for intestinal evacuation are called cathartics. They are substances that promote bowel movements and help relieve constipation by stimulating the intestines to expel their contents. Carminatives (option b) are used to relieve gas and bloating in the digestive tract. Astringents (option c) are used to constrict tissues and reduce secretions, typically not for intestinal evacuation. Antiprotozoal drugs (option d) are used to treat infections caused by protozoa, not for intestinal evacuation.
25. If gut motility is increased then:
a. Drug absorption is decreased
b. Drug absorption is increased
c. Drug absorption is not affected
d. Nothing definite can be said.
Answer: a. Drug absorption is decreased
Description:When gut motility is increased (i.e., the movement of contents through the gastrointestinal tract occurs more rapidly), it can lead to decreased drug absorption. This is because the drug may spend less time in contact with the absorbing surfaces of the intestines, reducing the opportunity for absorption. In conditions of very fast gut motility, some drugs may not be absorbed effectively, which can impact their therapeutic effectiveness.
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