NATIONAL AND STATE NURSING EXAM- MCQ _MG_00 196
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1. Verapamil is:
a. Beta adrenergic blocker
b. H2 receptor antagonist
c. Cardiac glycoside
d. Calcium channel blocker.
Answer: d. Calcium channel blocker.
Description:Verapamil is a calcium channel blocker (option d). It is commonly used to treat conditions like high blood pressure, angina (chest pain), and certain heart rhythm disorders by blocking calcium ions from entering the cells of the heart and blood vessels, which can help relax and dilate blood vessels and reduce the workload on the heart. It is not a beta-adrenergic blocker, H2 receptor antagonist, or cardiac glycoside.
2. Dobutamine causes:
a. Increased cardiac output
b. Marked increase in HR
c. Increased total peripheral resistance
d. Marked increase in a BP
Answer: d. Marked increase in a BP
Description:Dobutamine is a medication that primarily increases cardiac output. It is a synthetic catecholamine that acts as a beta-1 adrenergic receptor agonist, which means it stimulates the heart to beat more forcefully and increases cardiac output. While it can also lead to a mild increase in heart rate, its primary effect is to improve cardiac function and increase the amount of blood pumped by the heart, making option a the most appropriate choice. It does not typically cause a marked increase in blood pressure (option d) or an increase in total peripheral resistance (option c).
3. A 53-year-old male patient is brought into emergency room with acute myocardial infarction. Which of the following drug should be administered first?
a. ACE inhibitor
b. Aspirin
c. Calcium channel blocker
d. Statin
Answer: b. Aspirin
Description:Aspirin is often administered as soon as possible in cases of suspected heart attack because it helps prevent further blood clot formation by inhibiting platelet aggregation. This can help to reduce the extent of the heart muscle damage during a heart attack. It is a standard part of the initial treatment protocol for acute myocardial infarction. While other medications like ACE inhibitors, calcium channel blockers, and statins may be used later in the treatment plan for managing heart attacks and preventing future cardiac events, aspirin is the initial choice for its immediate antiplatelet effects to improve blood flow to the heart.
4. Which of the following instruction is appropriate in regard to nitroglycerine (NTG) for a patient with angina pectoris?
a. To take it before meals
b. To take with a glass of water
c. To store in amber colored bottle and keep it away from sunlight
d. None of the above.
Answer: c. To store in amber colored bottle and keep it away from sunlight
Description:Nitroglycerine is a medication that is sensitive to light and heat, so it should be stored in a cool, dark place, typically in an amber-colored bottle to protect it from light exposure. This helps maintain the stability and effectiveness of the medication. Options a and b do not pertain to storage instructions for nitroglycerine.
5. Which of the following is an early indication of digitalis toxicity?
a. Visual aberration
b. Fatigue
c. Seizures
d. Headache.
Answer: a. Visual aberration
Description:Digitalis toxicity can affect the eyes and lead to visual disturbances such as blurred or yellowed vision, seeing halos around lights, or other visual aberrations. This is known as "yellow vision" and can be an early sign of digitalis toxicity. Other symptoms of digitalis toxicity can include nausea, vomiting, fatigue, confusion, and irregular heart rhythms. Seizures and headaches are less common early signs of digitalis toxicity.
6. Atenolol is a/an:
a. α-adrenergic blocker
b. β-blocker
c. Anticholinergic agent
d. Cholinergic agent
Answer: b. β-blocker
Description:Atenolol is a beta-blocker medication commonly used to treat conditions such as hypertension (high blood pressure) and angina (chest pain). It works by blocking the effects of adrenaline on the beta receptors, specifically the beta-1 receptors in the heart. This results in a decrease in heart rate and blood pressure, making it effective in managing these conditions. It is not an α-adrenergic blocker, anticholinergic agent, or cholinergic agent.
7. Which of the following is not indicated in digitalis poisoning?
a. Potassium
b. Hemodialysis
c. Phenytoin
d. Lidocaine
Answer: b. Hemodialysis
Description:Hemodialysis is generally not indicated in cases of digitalis (digoxin) poisoning. Digitalis poisoning is typically managed with other treatments, such as the administration of antidotes like Digoxin-specific antibody fragments (Digoxin-specific antibody therapy or Digoxin-specific Fab fragments), which can bind to and neutralize the digitalis, as well as supportive care to manage symptoms and stabilize electrolyte imbalances. Potassium supplementation (option a) may be used to correct low potassium levels that can occur as a result of digitalis toxicity. Phenytoin (option c) and lidocaine (option d) may be considered to manage certain cardiac arrhythmias associated with digitalis toxicity. Hemodialysis is generally reserved for cases of severe toxicity or when other treatments have not been effective, as it can help remove digitalis from the bloodstream, but it is not the first-line treatment.
8. Which of the following is a protective lipoprotein?
a. LDL
b. IDL
c. VLDL
d. HDL
Answer: d. HDL
Description:HDL (High-Density Lipoprotein) is often referred to as the "good" cholesterol because it acts as a protective lipoprotein. HDL helps remove excess cholesterol from the bloodstream and transport it to the liver for processing and excretion, which can reduce the risk of cholesterol buildup in the arteries and lower the risk of heart disease.
9. The action of cardiotonic is to:
a. Decrease the force of contraction of heart
b. Increase the force of contraction of heart
c. Treat rheumatic heart disease.
d. Treat primary hypertension.
Answer: b. Increase the force of contraction of heart
Description:Cardiotonic agents, also known as positive inotropes, work by increasing the strength and force of cardiac muscle contractions. This can help improve the pumping function of the heart, which is beneficial in conditions such as heart failure or certain arrhythmias where the heart's pumping ability is compromised. They are used to increase cardiac output by enhancing the contraction of the heart muscle. Options c and d are unrelated to the action of cardiotonic agents.
10. Which of the following drug would be least effective in lowering a client’s serum potassium level?
a. Glucose and insulin
b. Polystyrene sulfonate
c. Calcium gluconate
d. Aluminum hydroxide.
Answer: d. Aluminum hydroxide.
Description:Among the options provided, aluminum hydroxide would be the least effective in lowering a client's serum potassium level. Aluminum hydroxide is an antacid and phosphate binder, but it is not typically used to lower elevated serum potassium levels. The other options are more relevant for managing high potassium levels: a. Glucose and insulin can help drive potassium into cells, temporarily lowering serum potassium levels. b. Polystyrene sulfonate (often referred to as Kayexalate) is a medication that can exchange sodium for potassium in the intestines, facilitating potassium removal through bowel movements. c. Calcium gluconate can be used to counteract the effects of high potassium on the heart and lower serum potassium levels. Aluminum hydroxide does not have a significant impact on potassium levels and is not used for potassium management.
11. A client with heart failure has digoxin ordered. What would the nurse expect to find when evaluating for the therapeutic effectiveness of this drug?
a. Diaphoresis with decreased urinary output
b. Increased heart rate with increase respiration
c. Improved respiratory status and increased urinary output
d. Decreased chest pain and decreased blood pressure.
Answer: c. Improved respiratory status and increased urinary output
Description:Digoxin is commonly prescribed in heart failure to improve cardiac function and reduce symptoms. It does this by increasing the strength of the heart's contractions (positive inotropic effect) and slowing down the heart rate (negative chronotropic effect). These actions can lead to improved cardiac output, better oxygenation, and increased urinary output, which can help alleviate symptoms of heart failure, including respiratory distress and fluid retention.
12. Digoxin (Digitalis) is the drug of choice for:
a. Angina pectoris
b. Congestive heart failure
c. Hypertension
d. Myocardial infarction
Answer: b. Congestive heart failure
Description:Digoxin, a cardiac glycoside used in the treatment of congestive heart failure. It acts by increasing the force of contraction ventricle.
13. The inotropic agent that can only be administered intravenously for heart failure is:
a. Digoxin
b. Dobutamine
c. Nifedipine
d. Atenolol.
Answer: b. Dobutamine
Description:Dobutamine is a cardiac inotrope useful in the acute treatment of congestive heart failure. Dobutamine can only be administered IV. Digoxin and Nifedipine can be administered orally. Atenolol is not inotropic agent.
14. The drug that increases both systolic and diastolic blood pressure for prolonged period is:
a. Dopamine
b. Ephedrine
c. Epinephrine
d. Dobutamine
Answer: b. Ephedrine
Description:The mechanism of action of ephedrine relies on its indirect stimulation of the adrenergic receptor system by increasing the activity of norepinephrine at the postsynaptic α and β receptors. It increase BP by direct and indirect action and has longer duration of action than epinephrine.
15. The side-effect of nitroglycerin is:
a. Vomiting
b. Diarrhea
c. Headache
d. Constipation.
Answer: c. Headache
Description:Headache is a common side effect of nitroglycerin. It is often referred to as a "nitroglycerin headache" and can occur shortly after taking the medication. This side effect is generally mild and temporary, but it is a well-known and common occurrence with nitroglycerin use. Vomiting, diarrhea, and constipation are less common side effects and are not typically associated with nitroglycerin use.
16. Digoxin acts by:
a. Increasing myocardial contractility
b. Decreasing myocardial contractility
c. Increasing heart rate
d. Increasing preload
Answer: b. Decreasing myocardial contractility
Description:Digoxin is a medication that primarily works by reducing the strength of contractions in the heart muscle (myocardial contractility). This can be beneficial in certain medical conditions, such as heart failure and some irregular heart rhythms, as it helps the heart pump blood more effectively and at a slower, steadier rate.
17. Antidote for digoxin toxicity is:
a. Digoxin immune Fab
b. Dobutamine
c. Flumazenil
d. Adrenaline
Answer: a. Digoxin immune Fab
Description:Digoxin immune Fab (ovine-derived antibodies) is used to counteract the toxic effects of digoxin in cases of digoxin overdose or toxicity. It binds to and neutralizes the excess digoxin in the body, helping to restore normal cardiac function and reduce the harmful effects of the medication.
18. A drug ending in the suffix (pril) is considered as:
a. Antidepressant
b. ACE inhibitors
c. Antifungal
d. Beat agonist
Answer: b. ACE inhibitors
Description:Medications with names ending in "-pril" are commonly angiotensin-converting enzyme (ACE) inhibitors. These drugs are commonly used to treat conditions such as high blood pressure and heart failure by inhibiting the ACE enzyme, which can help relax blood vessels and reduce blood pressure.
19. Which of the following drug is used as an antihypertensive?
a. Anticholinergics.
b. Mydriatics
c. Vasodilators.
d. Vasopressin
Answer: c. Vasodilators.
Description:Vasodilators are medications that help relax and widen blood vessels, which in turn reduces blood pressure. They are commonly used to treat hypertension (high blood pressure) by improving blood flow and reducing the workload on the heart. The other options listed (a. Anticholinergics, b. Mydriatics, d. Vasopressin) do not typically serve as antihypertensive drugs.
20. Propranolol can be used to allay anxiety associated with:
a. Chronic neurotic disorder
b. Schizophrenia
c. Short-term stressful situations.
d. Endogenous depression
Answer: c. Short-term stressful situations.
Description:Propranolol is a medication commonly prescribed for situational anxiety and performance anxiety. It can help reduce the physical symptoms of anxiety, such as a fast heart rate and trembling, especially in situations where anxiety may be acute and related to specific events or circumstances, such as public speaking or an important exam. It is not typically used for chronic neurotic disorders, schizophrenia, or endogenous depression.
21. Which of the following drug crosses blood brain barriers?
a. Glycopyrrolate
b. Dopamine
c. Streptomycin
d. Propranolol
Answer: d. Propranolol
Description:Propranolol crosses blood brain barrier. Dopamine, streptomycin and glycopyrrolate do not cross blood brain barrier.
22. All of the following drugs has to be avoided in combination with ACE inhibitors; EXCEPT:
a. Ibuprofen
b. Potassium supplements
c. Spironolactone
d. Theophylline
Answer: d. Theophylline
Description:Theophylline is not typically contraindicated with ACE inhibitors. However, ACE inhibitors can increase blood levels of theophylline, so careful monitoring of theophylline levels may be necessary when using them together. On the other hand, options a (Ibuprofen), b (Potassium supplements), and c (Spironolactone) can have interactions with ACE inhibitors that may lead to adverse effects, especially with regard to potassium levels.
23. Which of the following statement regarding propranolol is not true?
a. It is a B1 receptor specific blocker
b. It causes prominent postural hypotension
c. Has a very short half-life of 6 h
d. It has no effect on plasma
Answer: c. Has a very short half-life of 6 h
Description:Propranolol has a half life of 12 h
24. Which of the following antihypertensive drug contraindicated in the treatment of preeclampsia?
a. Magnesium sulfate
b. Labetalol
c. Nifedipine
d. ACE inhibitors
Answer: d. ACE inhibitors
Description:ACE inhibitors (Angiotensin-Converting Enzyme inhibitors) are generally contraindicated during pregnancy, including in the treatment of preeclampsia, as they can be harmful to the developing fetus. The other options (a. Magnesium sulfate, b. Labetalol, c. Nifedipine) are commonly used in the management of preeclampsia and are considered safer choices for pregnant individuals with high blood pressure in this context.
25. Which of the following adverse effect is associated with drug prazosin?
a. Sexual dysfunction
b. Dry mouth
c. Bradycardia
d. Both a and b
Answer: d. Both a and b
Description:Prazosin can commonly cause sexual dysfunction (option a) and dry mouth (option b) as side effects. These side effects are seen in some individuals taking prazosin for conditions like hypertension or benign prostatic hyperplasia. Bradycardia (option c) is not a typical adverse effect of prazosin.
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