NATIONAL AND STATE NURSING EXAM- MCQ _MG_00 207
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1. Following area the name of drugs and its antidotes. Which of the following combination is not correct?
a. Benzodiazepines-Flumazenil
b. Paracetamol-Acetyl cystine
c. Warfarin-protamine sulfate
d. Opioid-naloxone.
Answer: c. Warfarin-protamine sulfate
Description:Warfarin is an anticoagulant medication, and its antidote is not protamine sulfate. The antidote for warfarin is vitamin K. Protamine sulfate is used as an antidote for heparin, another anticoagulant medication.
2. Following are the types of poisoning and its antidotes. Which of the following combination is not correct?
a. Organophosphorus poisoning-Atropine sulfate
b. Heavy metal poisoning-Chelating agents
c. Methanol poisoning-Ethanol
d. Mushroom poisoning-Dopamine
Answer: d. Mushroom poisoning-Dopamine
Description:Dopamine is not the antidote for mushroom poisoning. The antidote for mushroom poisoning is typically activated charcoal or drugs like atropine and pralidoxime in cases of specific mushroom toxins.
3. Antidote for opioids is:
a. Atropine sulfate
b. Flumazenil
c. Neostigmine
d. Naloxone
Answer: d. Naloxone
Description:Naloxone is the antidote for opioid overdose. It is used to reverse the effects of opioids and can quickly restore normal respiration in individuals who have overdosed on opioids.
4. Simple herpes virus infection is treated with:
a. Stavudine
b. Ganciclovir
c. Acyclovir
d. Lamivudine
Answer: c. Acyclovir
Description:Acyclovir is the drug of choice in treating simple herpes virus infection.
5. The drug used by Health workers in the management of Acute respiratory illness is:
a. Cotrimoxazole
b. Chloramphenicol
c. Benzyl penicillin
d. Gentamycin
Answer: a. Cotrimoxazole
Description:Cotrimoxazole is a common antibiotic used to treat respiratory infections, including those caused by bacteria such as Streptococcus pneumoniae and Haemophilus influenzae. It is often used for the treatment of acute respiratory infections in healthcare settings.
6. Drug of choice for rheumatic fever is:
a. Cephalosporin
b. Penicillin
c. Streptomycin
d. Gentamycin
Answer: b. Penicillin
Description:Penicillin is the preferred antibiotic for the treatment of rheumatic fever to eradicate the streptococcal bacteria responsible for the infection and prevent further complications.
7. Drug of choice for syphilis is:
a. Ciprofloxacin
b. Cotrimoxazole
c. Doxycycline
d. Penicillin
Answer: d. Penicillin
Description:Penicillin, typically administered as benzathine penicillin G, is the primary and most effective treatment for syphilis. Other antibiotics may be used in cases of penicillin allergy or if penicillin is not available, but penicillin remains the preferred option for most cases of syphilis.
8. Drug of choice for syphilis in a pregnant lady is:
a. Penicillin
b. Azithromycin
c. Tetracycline
d. Ceftriaxone
Answer: a. Penicillin
Description:Penicillin is considered safe and effective for the treatment of syphilis in pregnant women and is the recommended treatment to prevent transmission of the infection to the unborn baby. Other antibiotics may not be as effective or safe during pregnancy.
9. Drug of choice in treatment of typhoid fever is:
a. Ampicillin
b. Ceftriaxone
c. Ciprofloxacin
d. Methicillin
Answer: b. Ceftriaxone
Description:Ceftriaxone is commonly used to treat typhoid fever due to its effectiveness against the causative bacterium, Salmonella Typhi. Other antibiotics like ciprofloxacin or azithromycin may also be used depending on the susceptibility of the bacteria and the patient's specific circumstances, but ceftriaxone is often preferred in severe cases or when the organism is resistant to other antibiotics.
10. Drug of choice for primary syphilis is:
a. Ampicillin
b. Benzathine penicillin
c. Erythromycin
d. Tetracycline
Answer: b. Benzathine penicillin
Description:Benzathine penicillin G is the preferred treatment for primary syphilis. It is typically administered as a single intramuscular injection and is highly effective at curing the infection at this stage. Other antibiotics may be used if the patient is allergic to penicillin, but penicillin is the first-line treatment for syphilis whenever possible.
11. Drug of choice for chemoprophylaxis against rheumatic fever is:
a. Penicillin V
b. Erythromycin
c. Benzathine penicillin
d. Procaine penicillin
Answer: c. Benzathine penicillin
Description:Benzathine penicillin G is used for secondary prophylaxis (preventive treatment) in individuals who have had rheumatic fever in the past to prevent recurrence. It is typically administered on a regular schedule to prevent the reoccurrence of the disease and its complications.
12. Drug of choice for prophylaxis of meningococcal meningitis is:
a. Penicillin
b. Erythromycin
c. Septran
d. Rifampicin
Answer: d. Rifampicin
Description:Rifampicin is commonly used for prophylaxis in close contacts of individuals with meningococcal meningitis to prevent the spread of the disease. It helps eliminate the Neisseria meningitidis bacteria from the nasopharynx and reduces the risk of transmission to others.
13. In leprosy, the best bactericidal agent is:
a. Clofazimine
b. Dapsone
c. Rifampicin
d. Ethionamide
Answer: c. Rifampicin
Description:Rifampicin is one of the most effective drugs for treating leprosy, and it is highly bactericidal against the causative bacteria, Mycobacterium leprae. It is commonly used in combination with other anti-leprosy drugs for effective treatment.
14. Drug of choice for malaria during pregnancy is:
a. Chloroquine
b. Quinine
c. Primaquine
d. Mefloquine
Answer: a. Chloroquine
Description:Chloroquine is often considered the drug of choice for the treatment of uncomplicated malaria in pregnant women, especially in regions where the malaria parasite is still sensitive to chloroquine. However, it's important to note that the choice of antimalarial drug may vary depending on the specific region and the type of malaria parasite present, so local guidelines should be followed. In some areas with drug-resistant strains of malaria, other medications like artemisinin-based combination therapies (ACTs) may be recommended. Pregnant women should always consult with a healthcare provider for the most appropriate and safe treatment.
15. Tetracycline is used for prophylaxis of:
a. Leptospirosis
b. Cholera
c. Meningitis
d. Brucellosis
Answer: b. Cholera
Description:Tetracycline antibiotics can be used as prophylaxis to prevent cholera infection in individuals who have been exposed to Vibrio cholerae, the bacterium responsible for cholera. It is not typically used for prophylaxis of the other conditions listed.
16. Treatment of drug resistant malaria is:
a. Quinine
b. Pyrimethamine
c. Mefloquine
d. All of these.
Answer: a. Quinine
Description:These drugs may be used to treat malaria in areas where there is resistance to other antimalarial medications like chloroquine or sulfadoxine-pyrimethamine. Pyrimethamine is sometimes used in combination therapy but is not usually a first-line treatment for drug-resistant malaria. Please note that the choice of treatment can change over time due to evolving drug resistance patterns, so it's essential to follow local and international guidelines for malaria treatment in a given region. Consultation with a healthcare professional is crucial for appropriate diagnosis and treatment of malaria.
17. The drug of choice for partial seizures is:
a. Carbamazepine
b. Barbiturates
c. Diazepam
d. Lamotrigine
Answer: a. Carbamazepine
Description:Carbamazepine is the drug of choice for the treatment of partial seizures. It is also used as an antimanic drug.
18. Drug of choice in treatment of partial complex seizures:
a. Carbamazepine
b. Sodium valproate
c. Ethosuximide
d. Phenytoin
Answer: a. Carbamazepine
Description:Carbamazepine is an antiepileptic drug often prescribed for the treatment of partial complex seizures. It helps control seizures by stabilizing the electrical activity in the brain. The choice of medication may also depend on factors such as the patient's age, other medical conditions, and potential side effects, so it's important to consult with a healthcare provider for a personalized treatment plan.
19. Drug of choice in acute central anticholinergic syndrome is:
a. Neostigmine
b. Physostigmine
c. Tacrine
d. 4-amino pyridine.
Answer: b. Physostigmine
Description:Physostigmine is a cholinesterase inhibitor and is used to reverse the effects of anticholinergic toxicity in cases of acute central anticholinergic syndrome. It helps to increase the availability of acetylcholine in the central nervous system, counteracting the anticholinergic effects and alleviating symptoms. However, it should only be administered by trained healthcare professionals in appropriate clinical settings, as it can have side effects and should be used judiciously.
20. Drug used for postoperative reversal of muscular paralysis:
a. Neostigmine
b. Pyridostigmine
c. Physostigmine
d. D tubocurarine.
Answer: a. Neostigmine
Description:Neostigmine is a cholinesterase inhibitor that helps reverse the effects of neuromuscular-blocking drugs like tubocurarine. It increases the levels of acetylcholine at the neuromuscular junction, which helps restore muscle function. It is commonly used in combination with atropine to prevent excessive cholinergic stimulation and side effects.
21. Drug of choice is treatment of myasthenia gravis is:
a. d-tubocurarine
b. Hexamethonium
c. Pyridostigmine
d. Gallamine
Answer: c. Pyridostigmine
Description:Pyridostigmine is an acetylcholinesterase inhibitor used to improve muscle strength and function in individuals with myasthenia gravis. It helps increase the availability of acetylcholine at the neuromuscular junction, which improves muscle contraction and alleviates the symptoms of myasthenia gravis. It is the mainstay of treatment for this condition.
22. Drug of choice in nocturnal enuresis is:
a. Imipramine
b. Diazepam
c. Amoxapine
d. Desmopressin
Answer: d. Desmopressin
Description:Desmopressin is a synthetic hormone that reduces urine production and is often used to treat nocturnal enuresis, especially in children. It helps decrease the frequency of nighttime bedwetting episodes. Other medications like imipramine may be considered in certain cases, but desmopressin is generally preferred due to its effectiveness and safety profile for this condition.
23. Drug used in the treatment of attention deficit hyperactivity disorder (ADHD) is:
a. Carbamazepine
b. Levodopa
c. Methylphenidate
d. Diazepam
Answer: c. Methylphenidate
Description:Methylphenidate is a commonly prescribed medication for the treatment of ADHD. It helps improve attention, focus, and impulse control in individuals with ADHD. Other medications, such as certain types of amphetamines or atomoxetine, may also be prescribed depending on the individual's specific needs and response to treatment. Treatment decisions should be made in consultation with a healthcare provider.
24. Drug of choice in theophylline poisoning:
a. Cortisone
b. Propranolol
c. Thyroxine
d. Phenytoin
Answer: b. Propranolol
Description:Propranolol is a beta-blocker that can be used to treat the symptoms of theophylline toxicity, such as rapid heart rate (tachycardia) and cardiac arrhythmias. It helps to counteract the stimulatory effects of theophylline on the heart and can be beneficial in managing the overdose. However, treatment for theophylline poisoning should be carried out under the guidance of a healthcare professional.
25. Drug of choice for ascariasis:
a. Piperazine citrate
b. Bephenium hydroxynaphthoate
c. Mebendazole
d. Albendazole
Answer: d. Albendazole
Description:Albendazole is an antiparasitic medication commonly used to treat a variety of parasitic infections, including ascariasis. It is effective in killing the adult worms in the intestines and is often administered as a single dose. Other medications like mebendazole may also be used for the treatment of ascariasis, but albendazole is frequently preferred due to its effectiveness and broad-spectrum activity against various parasitic worms.
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