NATIONAL AND STATE NURSING EXAM- MCQ _MG_00 228
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1. DOTS is a comprehensive strategy to cure TB. The primary element of DOTS is:
a. Sputum microscopy services.
b. Regular drug supply to the patients
c. Health workers counsel and observe their patients swallow each anti-TB medication and monitor progress until cured
d. Political will in terms of manpower
Answer: c. Health workers counsel and observe their patients swallow each anti-TB medication and monitor progress until cured
Description:The five elements of DOTS are political commitment with increased and sustained financing case detection through quality assured bacteriology, standardized treatment with supervision, effective drug supply and monitoring/evaluation system and impact measurement.
2. Disease which is also known as barometer of social welfare is:
a. TB
b. Typhoid
c. Cholera
d. HIV/AIDS
Answer: a. TB
Description:The disease that is often referred to as the "barometer of social welfare" is tuberculosis, which is represented by option (a). This term is used because the prevalence and impact of tuberculosis in a society can reflect the overall state of social and healthcare conditions. In regions with better social welfare and healthcare systems, the incidence of tuberculosis tends to be lower, while in areas with poorer social welfare and healthcare, tuberculosis can be more widespread. So, the answer is (a) TB.
3. What of the following disease is known as “Barometer of social welfare�
a. Leprosy
b. Tuberculosis
c. Cholera
d. Malaria
Answer: b. Tuberculosis
Description:The disease that is often referred to as the "barometer of social welfare" is tuberculosis, which is represented by option (b). This term is used because the prevalence and impact of tuberculosis in a society can reflect the overall state of social and healthcare conditions. In regions with better social welfare and healthcare systems, the incidence of tuberculosis tends to be lower, while in areas with poorer social welfare and healthcare, tuberculosis can be more widespread. So, the answer is (b) Tuberculosis.
4. The most appropriate test to assess the prevalence of tuberculosis infection in a community is:
a. Mass miniature Radiography
b. Sputum examination
c. Tuberculin test
d. Clinical examination
Answer: c. Tuberculin test
Description:The most appropriate test to assess the prevalence of tuberculosis infection in a community is the tuberculin test, which is represented by option (c). The tuberculin test, also known as the Mantoux test, involves injecting a small amount of purified protein derivative (PPD) under the skin and then measuring the skin reaction a few days later. This test helps identify individuals who have been exposed to the tuberculosis bacterium and have developed an immune response to it, even if they do not have active tuberculosis disease. It is a valuable tool for assessing the prevalence of latent tuberculosis infection in a community.
5. Incidence of TB in community is measured by:
a. Sputum smear positivity
b. Positive tuberculin test
c. Sputum culture
d. Mantoux test positive
Answer: a. Sputum smear positivity
Description:The incidence of TB in a community is typically measured by the percentage of individuals who test positive for TB through sputum smear microscopy, which is represented by option (a). Sputum smear microscopy is a diagnostic test used to detect active pulmonary tuberculosis by examining sputum samples for the presence of the tuberculosis bacterium (Mycobacterium tuberculosis). It helps identify individuals who have active TB disease and are capable of transmitting the infection to others. Therefore, it is a key method for assessing the incidence of tuberculosis in a community.
6. Full form of DOTS chemotherapy is:
a. Directly observed treatment short course
b. Digitally operated treatment service
c. Directly observed therapy supervised
d. Directly observed treatment supervised
Answer: a. Directly observed treatment short course
Description:The full form of DOTS chemotherapy is: a. Directly observed treatment short course
7. Which of the following drugs in DOTS therapy can cause deafness?
a. Ethambutol
b. Isoniazid
c. Rifampicin
d. Streptomycin
Answer: d. Streptomycin
Description:The drug in DOTS (Directly Observed Treatment Short Course) therapy that can cause deafness as a potential side effect is: d. Streptomycin
8. Which of the following tests is done to test the efficiency of pasteurization of milk?
a. Coliform count
b. Methylene blue
c. Reduction test
d. Indicator test
Answer: a. Coliform count
Description:This test measures the presence of coliform bacteria in milk, which is an indicator of whether pasteurization has successfully killed harmful microorganisms. If the coliform count is low, it suggests that the pasteurization process was effective in making the milk safe for consumption.
9. Which of the following tests is done to check the presence of tuberculosis in human being?
a. Welson Blot
b. Widal test
c. Mantoux test
d. ELISA test
Answer: c. Mantoux test
Description:The Mantoux test, also known as the tuberculin skin test, is used to detect whether a person has been exposed to the tuberculosis bacterium by measuring the skin's reaction to a specific antigen derived from Mycobacterium tuberculosis. This test helps diagnose latent tuberculosis infection (LTBI) or confirm active tuberculosis disease.
10. Case finding in RNTCP is based on:
a. Sputum culture
b. Sputum microscopy
c. X ray chest
d. Mantoux test/PCR
Answer: b. Sputum microscopy
Description:Sputum microscopy involves examining sputum samples under a microscope to detect the presence of acid-fast bacilli (AFB), which are characteristic of Mycobacterium tuberculosis, the bacterium that causes tuberculosis. This method is crucial for diagnosing and identifying TB cases, especially in areas with limited resources.
11. All among the following are bactericidal ATT drugs; EXCEPT:
a. Rifampicin
b. Ethambutol
c. Streptomycin
d. Ethambutol
Answer: a. Rifampicin
Description:Among the following drugs used to treat tuberculosis (ATT drugs), all of them except one have the ability to kill bacteria directly. The term for drugs that can kill bacteria is "bactericidal." Here are the options and their bactericidal status: a. Rifampicin - Bactericidal b. Ethambutol - Bacteriostatic (inhibits bacterial growth but doesn't directly kill them) c. Streptomycin - Bactericidal d. Ethambutol - Bacteriostatic
12. Anti-tubercular drug contraindicated in pregnancy is:
a. Isoniazid
b. Rifampicin
c. Streptomycin
d. Ethambutol
Answer: c. Streptomycin
Description:The anti-tubercular drug contraindicated in pregnancy is Streptomycin (c). It can have harmful effects on the developing fetus, and therefore, it is generally avoided during pregnancy. The other options, Isoniazid (a), Rifampicin (b), and Ethambutol (d), may be used in the treatment of tuberculosis during pregnancy under the guidance of a healthcare professional, as their benefits may outweigh the risks in certain cases.
13. Why TB patient is recommended a regiment of 4 drugs on 1st visit?
a. To avoid emergence of resistance
b. To avoid side effects
c. To cure disease early
d. None of the above
Answer: a. To avoid emergence of resistance
Description:The reason TB patients are recommended a regimen of 4 drugs on their first visit is primarily to avoid the emergence of resistance (option a). This approach is known as Directly Observed Treatment, Short-course (DOTS), which is a standard protocol for tuberculosis treatment recommended by the World Health Organization (WHO). By using a combination of drugs, especially in the initial phase of treatment, the risk of TB bacteria developing resistance to a single drug is significantly reduced. TB bacteria can mutate and become resistant to individual drugs if they are exposed to them without being properly targeted. Using a combination of drugs from the start helps ensure that multiple mechanisms in the bacteria are targeted simultaneously, making it much harder for them to develop resistance. While avoiding side effects (option b) and curing the disease early (option c) are important goals of TB treatment, the primary reason for using a combination of drugs is to prevent drug resistance. However, it's worth noting that using multiple drugs also contributes to more effective treatment and can help minimize side effects by distributing the therapeutic load across different medications.
14. True about DOTS is:
a. Drugs are given under supervision
b. Streptomycin is always given in first 2 months
c. Intermittent regiment is followed
d. Same regimen is given in all patient
Answer: a. Drugs are given under supervision
Description:In DOTS, tuberculosis patients are required to take their medications under the direct observation of a healthcare worker or a trained supervisor. This ensures that patients are adhering to the treatment regimen, which is crucial for the effectiveness of TB treatment and preventing the development of drug-resistant strains of TB. The other statements (b, c, d) are not necessarily true for all DOTS programs. The use of Streptomycin in the first two months (b), the specific regimen (d), and the use of intermittent regimens (c) can vary depending on the specific guidelines and protocols followed in different regions and healthcare settings.
15. Multidrug resistance in TB is defined as resistance to:
a. Streptomycin, Rifampicin and isoniazid
b. Streptomycin and Rifampicin
c. Isoniazid and Rifampicin
d. Streptomycin and Isoniazid
Answer: c. Isoniazid and Rifampicin
Description:Multidrug-resistant tuberculosis (MDR-TB) is a form of tuberculosis in which the TB bacteria are resistant to at least two of the most powerful first-line anti-TB drugs, which are Isoniazid and Rifampicin. This means that individuals with MDR-TB do not respond to standard TB treatment, and more complex and prolonged treatment regimens are required.
16. Anit-tubercular drug not given in children <6 years of age
a. Isoniazid
b. Rifampicin
c. Streptomycin
d. Ethambutol
Answer: d. Ethambutol
Description:Ethambutol is generally avoided in very young children because they may have difficulty communicating any vision-related side effects that can occur with this medication. This drug can cause visual disturbances, which may be difficult for young children to express, making it challenging to monitor for side effects in this age group. Other anti-TB drugs like Isoniazid, Rifampicin, and Streptomycin are often used in the treatment of tuberculosis in children, but the choice of medication and dosage should be determined by a healthcare professional based on the specific circumstances of the child.
17. What type of toxin is produced by Clostridium tetani?
a. Exotoxin
b. Endotoxin
c. Organic toxin
d. Inorganic toxin
Answer: a. Exotoxin
Description:The toxin produced by Clostridium tetani is an exotoxin (option a). Exotoxins are toxic proteins that are released by certain bacteria into their surrounding environment. In the case of Clostridium tetani, the exotoxin produced is called tetanospasmin, which is responsible for causing the symptoms of tetanus when it enters the body's nervous system.
18. Strategy for prevention of neonatal tetanus include all; EXCEPT:
a. TT to all females in reproductive age group
b. Giving penicillin to all neonates
c. 2 doses of TT to all unimmunized pregnant women
d. Three cleans
Answer: b. Giving penicillin to all neonates
Description:a. TT (Tetanus Toxoid) vaccination to all females in the reproductive age group. c. Providing 2 doses of TT to all unimmunized pregnant women. d. Promoting clean practices during childbirth, commonly referred to as "Three Cleans," which involve cleaning the hands, perineum, and the newborn's cord area. Option b, "Giving penicillin to all neonates," is not a typical part of neonatal tetanus prevention. Neonatal tetanus prevention primarily focuses on maternal vaccination with TT, clean delivery practices, and ensuring that pregnant women receive adequate immunization to pass on protection to their newborns through passive immunity. Penicillin is an antibiotic used to treat infections but is not a routine preventive measure for neonatal tetanus.
19. In Tetanus communicable period is:
a. 7 days
b. 10 days
c. 14 days
d. None of these
Answer: d. None of these
Description:Tetanus is not a communicable disease, meaning it cannot be transmitted from one person to another. Therefore, none of the options (a, b, c) apply to the communicable period for tetanus because there is no communicable period associated with this disease. Tetanus is caused by the introduction of the tetanus bacteria (Clostridium tetani) into a wound or injury, typically through contamination with soil or other materials containing the bacteria. It does not spread from person to person.
20. What reaction might occur due to tetanus vaccine?
a. Febrile seizures
b. Brachial neuritis
c. Hypotonic muscles
d. Encephalopathy
Answer: b. Brachial neuritis
Description:Brachial neuritis is a rare adverse event that has been associated with the tetanus vaccine. It involves inflammation of the brachial plexus, a network of nerves that control the muscles of the arm and hand. This condition can cause weakness and pain in the affected arm. It's important to note that while such reactions are possible, they are quite rare, and the benefits of tetanus vaccination in preventing tetanus far outweigh the risks of such adverse events. Other reactions listed (febrile seizures, hypotonic muscles, encephalopathy) are not typically associated with the tetanus vaccine.
21. The true statement regarding tetanus is:
a. 5 dose immunization provides lifelong immunity
b. TT affords not protection in the present injury
c. TT serves no use once 12 hours have elapsed following injury
d. TT and Ig may both be given in suspected tetanus
Answer: d. TT and Ig may both be given in suspected tetanus
Description:When someone has a suspected tetanus infection or a high-risk tetanus exposure (such as a dirty wound), both Tetanus Toxoid (TT) vaccination and Tetanus Immunoglobulin (Ig) may be administered. The TT vaccine helps boost immunity against tetanus, while Tetanus Immunoglobulin provides immediate passive immunity by providing preformed antibodies against the tetanus toxin. These two treatments are often given together in cases where tetanus is suspected or to individuals with inadequate or uncertain vaccination histories. The other statements (a, b, c) are not accurate: a. 5 dose immunization does not provide lifelong immunity; booster doses are required periodically to maintain immunity. b. TT (Tetanus Toxoid) does offer protection when administered after an injury to prevent tetanus infection. c. TT can still be useful even after 12 hours have elapsed following an injury; however, the earlier it's administered after an injury, the better.
22. The effective preventive measures for AIDS are use of condom which provides protection against
a. Inhibition of sperm action
b. Spermicidal action
c. Agglutination of spermatozoa
d. All of the above.
Answer: a. Inhibition of sperm action
Description:Preventive measure are used for AIDS in the use of male and female condoms which reduce the risk for spreading the disease by inhibiting the contact of sperm on vaginal wall. Condom is acting as a barrier between sperm and vaginal mucosal wall.
23. Intervention used under prevention of spreading of AIDS include:
a. Treating STD
b. Providing condoms
c. Behavior change communication
d. All of the above.
Answer: d. All of the above.
Description:All of the above components are used for preventing spread of HIV
24. Identify the sexually transmitted disease among the following;
a. Rabies virus
b. CMV
c. Retro virus
d. Adenovirus
Answer: c. Retro virus
Description:AIDS is caused by HIV (Human immunodeficiency viral). This virus belongs to lenti family and it affects the CD4T cell.
25. In tuberculosis combination of antimicrobials is used:
a. To delay development of resistance
b. To reduce toxicity
c. To broaden antibacterial spectrum
d. To prevent liberation of toxins from organism.
Answer: a. To delay development of resistance
Description:Combining multiple antimicrobial drugs in the treatment of tuberculosis helps to reduce the likelihood of the TB bacteria (Mycobacterium tuberculosis) developing resistance to any single drug. This approach is crucial in preventing the emergence of drug-resistant strains of TB, such as multidrug-resistant tuberculosis (MDR-TB) and extensively drug-resistant tuberculosis (XDR-TB). The simultaneous use of several drugs with different mechanisms of action makes it more difficult for the bacteria to develop resistance to all of them.
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